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According to the Institute for Functional Medicine, the Functional Medicine model is...

an individualized, patient-centered, science-based approach that empowers patients and practitioners to work together to address the underlying causes of disease and promote optimal wellness. It requires a detailed understanding of each patient’s genetic, biochemical, and lifestyle factors and leverages that data to direct personalized treatment plans that lead to improved patient outcomes.

By addressing root cause, rather than symptoms, practitioners become oriented to identifying the complexity of disease. They may find one condition has many different causes and, likewise, one cause may result in many different conditions. As a result, Functional Medicine treatment targets the specific manifestations of disease in each individual.

Barabási, Albert-László, Natali Gulbahce, and Joseph Loscalzo. Network medicine: a network-based approach to human disease. Nature reviews genetics 12, no. 1 (2011): 56.


Beidelschies, Michelle, Marilyn Alejandro-Rodriguez, Xinge Ji, Brittany Lapin, Patrick Hanaway, and Michael B. Rothberg. Association of the Functional Medicine Model of Care with Patient-Reported Health-Related Quality-of-Life Outcomes. JAMA network open 2, no. 10 (2019): e1914017-e1914017.


Bland, Jeffrey. Functional medicine: An operating system for integrative medicine. Integrative Medicine: A Clinician's Journal 14, no. 5 (2015): 18.


Bland, J. S., D. M. Minich, and B. M. Eck. A systems medicine approach: Translating emerging science into individualized wellness. Advances in medicine 2017 (2017).

Bland, Jeffrey. Systems biology, functional medicine, and folates. Alternative therapies in health and medicine 14, no. 3 (2008): 18.


Bland, Jeffrey S. The Natural Roots of Functional Medicine. Integrative Medicine: A Clinician's Journal 17, no. 1 (2018): 12.


Henningsen, Peter, Stephan Zipfel, and Wolfgang Herzog. Management of functional somatic syndromes. The Lancet 369, no. 9565 (2007): 946-955.


Hood, Leroy, and Qiang Tian. Systems approaches to biology and disease enable translational systems medicine. Genomics, proteomics & bioinformatics 10, no. 4 (2012): 181-185.


Loscalzo, Joseph, and Albert‐Laszlo Barabasi. Systems biology and the future of medicine. Wiley Interdisciplinary Reviews: Systems Biology and Medicine 3, no. 6 (2011): 619-627.


Tillisch, K. Complementary and alternative medicine for functional gastrointestinal disorders. Gut 55, no. 5 (2006): 593-596.

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